By way of an introduction, the aim of the site is to create a log of experimental work. The information will be made public through Google, so we should make sure that anything pre-publication that is sensitive is not revealed too soon. On the other hand, since most of the experimental work is not of this kind and the sharing of ideas and methods etc is more likely to stimulate our research, I would encourage free exchange between us. If in doubt email me first.
To begin with, there is a need to consider how we develop our thinking and experimental approaches to defining protein complexes. Mainly how do we address the issue of interactors over contaminants? And how do we design functional experiments to test the model of any of our complexes. How do we deal with stable complexes and those that are much more dynamic. Any thoughts? Any key references? Any comments on the recent Nature paper from Cellzome?
No comments:
Post a Comment